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Our Innovations

Issued Patents

  • US12042508 - 7/23/2024 - Wren E. Michaels, Michelle Hastings - Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
  • US11814392B2 - 11/14/2023 - June Mayor, Ronald Kaplan, Shivaputra Patil - Chromenopyridine-based Compounds and Methods of Making and Use Thereof
  • US11786507B2 - 10/17/2023 - Johnny He - Methods of Treating HIV-Associated Neurological Disorders (Hand)
  • US11559231B2- 1/24/2023 - Joanna Dabrowska - System and Method for Determining a Discrimination Index for Fear-Potentiated Startle
  • US11219677B2 - 1/11/2022 -Kwang Poo Chang, et al. - Immunotherapy of Canine Leishmaniasis
  • US11116785B2 - 9/14/2021 - Michelle Hastings - Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
  • US10822325B2 - 11/3/2020 - Jun-Yong Choe, et al. - Human GLUT5 Specific Inhibitor Using Virtual Screening and in Vitro Transport Evaluation
  • US10787669B2 - 9/29/2020 - Michelle Hastings, et al. - Antisense Compounds Targeting Leucine-RICH Repeat Kinase 2 (LRRL2) for the Treatment of Parkinson Disease
  • US10729370 - 8/4/2020 - Lin Fang and Sai Yalla - Mobile Sensor System and Methods for Use
  • US10721993 - 7/28/2020 - Noah Rosenblatt, Ryan Crews, et al. - Intelligent Offloading Insole Device
  • US10544417B2 - 1/28/2020 - Michelle Hastings - Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
  • US10525076B2 - 1/24/2020 - Michelle Hastings - Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
  • US10472634B2 - 11/12/2019 - Michelle Hastings, et al. - Antisense Compounds Targeting Apolipoprotein E Receptor 2 (Alzheimer)
  • US10370667B2 - 8/6/2019 - Michelle Hastings, et al. - Antisense Compounds Targeting Leucine-RICH Repeat Kinase 2 (LRRL2) for the Treatment of Parkinson Desease
  • US10070648 - 9/11/2018 - Kwang Poo Chang - Photodynamic Insecticides
  • US10028906B2 - 7/24/2018 - Bruce Riser - Method and Kit for Treating a Solid Tumor and Associated Desmoplasia
  • US10351608B2 - 7/16/2019 -  Bruce Riser - CCN3 and CNN3 Peptides and Analogs Thereof for Therapeutic Use
  • US10011578B2 - 7/3/2018 - Grace Stutzmann - Compounds for Stabilizing Ryanodine Receptors from Aberrant Levels of Calcium Release  
  • US9970056 - 5/15/2018 - Judith Potashkin - Methods and Kits for Diagnosing, Prognosing and Monitoring Parkinsons Disease
  • US9839389 - 12/12/2017 - Karen Stevens - Foot-Strength Test Device and Methods for Use
  • US9840709 - 12/12/2017 -  Michelle Hastings - Antisense Compounds Targeting Genes Associated With Cystic Fibrosis
  • US9840710 - 12/12/2017 -  Michelle Hastings - Antisense Compounds Targeting Leucine-RICH Repeat Kinase 2 (LRRL2) for the Treatment of Parkinson Desease
  • US9827478B1 - 11/28/2017 -  Bijan Najafi, et al. - Providing Visual Motion Feedback Based on Sensor Data
  • US9725429 B2 - 8/8/2017 - Grace Stutzmann - Furan-based Compounds for Stabilizing Ryanodine Receptors from Aberrant Levels of Calcium Release and Method for Treating Alzheimer's Disease with these Compounds
  • US9556434 - 1/31/2017 - Michelle Hastings - Antisense oligonucleotides that target a cryptic splice site in Ush1c as a therapeutic for usher syndrome
  • US9532961 - 1/3/2017 - Darryl Peterson - A method and kit for administering gamma-glutamyl-D-cysteine for the prevention of reperfusion injury following ischemic stroke  
  • US9353371 - 5/31/2016 - Michelle Hastings, et al. - Antisense Compounds Targeting Genes Associated with usher syndrome
  • US9327017 - 5/3/2016 - Kwang-Poo Chang, Sujoy Dutta - Leishmania-based carrier for vaccine delivery
  • US9114112 - 8/25/2015 - Bruce Riser - CNN3 and CNN3 peptides and analogs thereof for therapeutic use
  • US9102645 - 8/11/2015 - Grace Stutzman - Compounds for stabilizing ryanodine receptors from aberrant levels of calcium release
  • US8979665B1 - 3/17/2015 - Bijan Najafi, et al. - Providing Motion Feedback Based on User Center of Mass
  • US8841436 - 9/23/2014 -Judith Potashkin, et al. - Screening, diagnosing, treating and prognosis of pathophysiologic status by RNA regulation
  • US8772468 - 7/8/2014 - Judith Potashkin - Splice variant specific messenger RNA transcripts as biomarkers of Parkinson's disease
  • US8753275B2 - 6/17/2014 - Bijan Najafi, et al. - Intelligent Device to Monitor And Remind Patients With Footwear, Walking Aids, Braces, Or Orthotics
  • US8648053 - 2/11/2014 - Michelle Hastings - Antisense oligonucleotides that target a cryptic splice site in USH1C as a therapeutic for usher syndrome
  • US8518886 - 8/27/2013 - Darryl Peterson - Cytoprotective therapeutic agents for the prevention of reperfusion injury following ischemic stroke
  • US8518395 - 8/27/2013 - Bruce Riser - CCN3 peptides and analogs thereof for therapeutic use 
  • US8133860 - 3/13/2012 - Raul Gazmuri - Facilitation of resuscitation from cardiac arrest by erythropoietin
  • US8105257 - 1/31/2012 - Erin Klein, et al. - Extremity stress attenuation modality with resistance-mechanism engaging member
  • US8067366 - 11/29/2011 - Raul Gazmuri - Facilitation of resuscitation from cardiac arrest by erythropoietin
  • US7956037 - 6/7/2011 - Darryl Peterson - Cytoprotective therapeutic agents for the prevention of reperfusion injury following ischemic stroke 
  • US7780949 - 8/24/2010 - Bruce Riser - Regulation of CCN2 by CCN3 and its therapeutic and diagnostic potential in fibrosis, sclerosis and other diseases
  • US7261887 - 8/28/2007 - Kwang-Poo Chang, Sujoy Dutta. - Leishmania as carriers for the delivery of proteins and peptides 
  • US7238347 - 7/3/2007 - Kwang-Poo Chang, Sujoy Dutta. - Suicidal mutant Leishmania vaccine 

Pending Patents

  • 18/944,999 - 11/12/2024 - Holly Hunsberger - Wearable Health Tracker for Rodents
  • PCT/US24/53253 - 10/28/2024 - Michelle Hastings, et al. - Compounds and Methods for Modulating CLN3 Expression
  • 18/188932 - 3/23/2023 - Johnny He - Dual Promoter-Driven and Dual Reporter-Expressing SARS-COV-2 Replicons and Methods of Use
  • 17/936,539 - 9/29/2022 - Noah Rosenblatt, Sai Yalla, Sunjung Kim - Durability Test System for Repetitive Loading of a Prosthetic Socket
  • PCT/US2022/043775 - 9/16/2022 - John Buolamwini, et al. - Benzylthiphane Derivatives
  • 17/371,427 - 7/9/2021 - Raul Gazmuri - Gliflozins and a Method for their Delivery during Resuscitation from Cardiac Arrest to Improve Survival Outcomes
  • 17/274,981 - 3/10/2021 - Michelle Hastings, et al. - Compounds and Methods For Modulating CLN3 Expression
  • 16/977,649 - 9/2/2020 - Michelle Hastings, et al. - Compounds and Methods for the Modulation of Amyloid Beta Precursor Protein
  • 16/888576 - 5/29/2020 - Kwang Poo Chang - Immunotherapy of Solid Tumors by Vaccination with Transgenicleishmania Expressing Cancer Vaccines
  • 16/511,103 - 7/15/2019 - Bruce Riser - CCN3 and CCN3 Peptides and Analogs Thereof for Therapeutic Use
  • PCT/EP2020/078295 - 10/8/2020 - Jun-Yong Choe, et al. - Variant of Gala Reductase and their Uses
  • 16/536,981 - 8/9/2019 - Michelle Hastings, et al. - Antisense Compounds Targeted to CLN3 and Uses Thereof