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Joseph M. Reynolds

Joseph M. Reynolds, PhD

Director, Center for Cancer Cell Biology, Immunology, and Infection

 

  • Joseph Reynolds - Director
    • The role of the IL-17 family of cytokines in autoimmune inflammation and mucosal immunity.
  • Najla Arshad
    • Investigating how ER chaperones regulate immune responses in health and disease and applying this knowledge to develop cancer immunotherapies.
  • Kwang Poo Chang
    • The Leishmania based photo-vaccines against infectious and malignant diseases.
  • Svetlana Dambaeva
    • Immune response at the maternal-fetal interface and analysis of immune mechanisms of infertility and recurrent pregnancy loss.
  • Joseph X. DiMario
    • The cellular and molecular mechanisms that regulate the development and differentiation of skeletal muscle fibers and their respective phenotypes.
  • Mirek Dundr
    • Compartmentalization of the nucleus as it contributes to genome function and regulates genome organization in cancer.
  • David N. Everly
    • Epstein-Barr virus (EBV) transforming protein and its role in manipulating cellular signaling pathways involved in tumor formation (Note: EBV is associated with Burkitt’s lymphoma, nasopharyngeal carcinoma, as well as certain types of Hodgkin disease and gastric cancers).
    • Constitutive inflammatory signaling in virally induced cancer and the role of viruses in multiple sclerosis.
  • Johnny J. He
    • HIV infection and pathogenesis in astrocytes.
    • Molecular mechanisms of HIV Tat protein neurotoxicity.
    • Tip110 and tumorigenesis.
  • Erin N. Howe
    • Molecular mechanisms driving metastatic breast cancer, particularly endosomal recycling as a mechanism driving breast cancer adaptation to the brain metastatic microenvironment.
  • Hongkyun Kim
    • Identification and characterization of genes responsible for neuromuscular diseases, including muscular dystrophies.
  • Ying Liu
    • HIV latency in astrocytes.
    • Tip110 and HIV gene transcription control.
  • Fabio Re
    • The role of toll-like receptors and inflammasomes during bacterial infections and vaccination.
  • Roxane Rohani
    • Effects of adjunctive treatments and antiretroviral therapies on lowering chronic inflammation and immune activation among persons living with HIV.
  • Neelam Sharma-Walia
    • Arachidonic acid pathway in KSHV pathogenesis.
    • The role of inflammatory COX-2 and lipoxins and anti-inflammatory leukotrienes role in inflammatory breast cancer and virus associated cancers.
  • Rahul Vijay
    • The precise role played by the early short-lived plasmablasts in various infections.
    • Identification of immunotherapeutic approaches to restrain infection-induced plasmablasts.
  • Justin Whalley
    • Methods for uncovering the quintessential features of gene expression, protein abundance, epigenetic profile and cell population datasets.
  • Carl White
    • Modulation of reactive oxygen species and calcium signaling pathways in the smooth muscle cells of resistance arterioles in mouse models of diabetes.