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Daniel A. Peterson, Ph.D.

Professor and Vice-Chairman
Department of Neuroscience
Chicago Medical School
Room 2.217B
Building: BSB
Phone: 847.578.3411
Fax: 847.578.8515

Selected Publications
(from over 65 peer-reviewed publications)

Gage, F. H., Coates, P.W., Palmer, T.D., Kuhn, H.G., Fisher, L.J., Suhonen, J.O., Peterson, D.A., Suhr, S.T., and Ray, J. (1995) Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain. Proc. Natl. Acad. Sci., USA 92:11879-11883.

Peterson, D.A., Lucidi-Phillipi, C.A., Murphy, D., and Gage, F.H. (1996) FGF-2 protects entorhinal layer II glutamatergic neurons from axotomy-induced death. Journal of Neuroscience 16(3):886-898.

Suhonen, J.O., Peterson, D.A., Ray, J. and Gage, F.H. (1996) Differentiation of adult-derived hippocampal progenitor cells into olfactory bulb neurons. Nature 383:624-627.

Peterson, D.A., Leppert, J.T., Lee, K-F., and Gage, F.H. (1997) Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75. Science 277(5327):837-838.

Kafri, T., Blömer, U., Peterson, D.A., Gage, F.H., and Verma, I. (1997) Sustained expression of genes delivered directly in liver and muscle by lentiviral vectors. Nature Genetics 17:314-317.

Eriksson, P.S., Perfilieva, E., Björk-Eriksson, T., Alborn, A-M., Nordborg, C., Peterson, D.A., and Gage, F.H. (1998) Neurogenesis in the adult human hippocampus. Nature Medicine 4(11):1313-1317.

Peterson, D.A. (1999) Quantitative histology using confocal microscopy: Implementation of unbiased stereology procedures. Methods: A Companion to Methods in Enzymology 18:493-507.

Peterson, D.A. (2002) Stem Cells in Brain Plasticity and Repair. Current Opinion in Pharmacology 2:34-42

Kaspar, B., Schaeffer, D.S., Erickson, D.A., Hinh, L., Gage, F.H., and Peterson, D.A. (2002) Rescue of specific projection neurons by retrograde anti-apoptotic gene delivery. Molecular Therapy 5:50-56.

Hallbergson, A.F., Gnatenco, C. and Peterson, D.A. (2003) Neurogenesis following brain injury: Managing a renewable resource for brain repair Journal of Clinical Investigation 112:1128-1133.

Peterson, D.A. (2004) The use of fluorescent probes in cell counting procedures. In Quantitative Methods in Neuroscience, Evans, S., Jansen, A.M., and Nyengaard, J.R. (Eds.) Oxford University Press pp. 85-114.

Bernal, G.M. and Peterson, D.A. (2004) Neural stem cells as therapeutic agents for age-related brain repair. Aging Cell 3:345-351.

Vega, C.J., and Peterson, D.A. (2005) Stem cell proliferative history in tissue revealed by temporal halogenated thymidine analog discrimination. Nature Methods 2:167-169.

Sondi, D., Peterson, D.A., Sanders, C.T., Rostkowski, A., Giannaris E.L., De, B., Grant, A., Lam, M., Hackett, N.R., Kaminsky, S.M., and Crystal, R.G. (2005) AAV2-Mediated CLN2 gene transfer to brains of rodents and non-human primates results in widespread TPP-I expression at distribution levels compatible with therapy for late infantile neuronal ceroid lipofuscinosis. Gene Therapy 12:1618-1632.

Lazarov, O., Peterson, L.D., Peterson, D.A., and Sisodia, S.S. (2006) Expression of FAD-linked PS1∆E9 enhances perforant pathway lesion-induced neuronal cell death in the entorhinal cortex. Journal of Neuroscience 26:429-434.

Chadashvili, T. and Peterson, D.A. (2006) Cytoarchitecture of fibroblast growth factor receptor 2 (FGFR-2) immunoreactivity in astrocytes of neurogenic and non-neurogenic regions of the young adult and aged rat brain. Journal of Comparative Neurology 498:1-15.

Sanders, C.T., Sanchez, N., Ballantyne, J., and Peterson, D.A. (2006) Laser microdissection for pure separation of spermatozoa from epithelial cells for STR analysis. Journal of Forensic Science 51:748-757.

Sondi, D., Hackett, N.R., Travis, K., Peterson, D.A., and Crystal, R.G. (2007) Impact of intracranial administration of CLN2 gene mediated by Rhesus Macaque derived AAVrh.10 vector on performance in CLN2 knockout mice. Molecular Therapy 15:481-491.

Thomas, R.M., Hotsenpiller, G., and Peterson, D.A. (2007) Acute psychosocial stress reduces cell survival in adult hippocampal neurogenesis but not initial proliferation. Journal of Neuroscience 27:2734-2743.

Sondhi, D., Hackett, N.R., Peterson, D.A., Stratton, J., Baad, M., Travis, K.M., Wilson, J.M., and Crystal, R.G. (2007)  Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector.  Molecular Therapy 15:481-491.

Sondhi, D., Peterson, D.A., Edelstein, A.M., del Fierro, K., Hackett, N.R., and Crystal R.G. (2008)  Survival advantage of neonatal CNS gene transfer for late infantile neuronal ceroid lipofuscinosis.  Experimental Neurology 213:18-27.

Thomas, R.M., and Peterson D.A. (2008)  Even neural stem cells get the blues:  modulation of neurogenesis and gene expression in animal models of depression.  Gene Expression 14:183-193.

Kuhn, H.G., and Peterson, D.A. (2008)  Detection and Phenotypic Characterization of Adult Neurogenesis. in Gage, F.H., Kempermann, G. and Song, H. (Eds.) Adult Neurogenesis, 2nd Edition, Cold Spring Harbor Press, New York, pp. 25-47.

Bernal, G.M., and Peterson, D.A. (2009)  Synaptic plasticity:  Neuronogenesis and stem cells in normal brain aging.  In Larry R. Squire, Editor-in-Chief, Encyclopedia of Neuroscience, Academic Press, Oxford, 2008, Pages 769-772.

Bernal, G.M., and Peterson, D.A. (2009)  Neurogenesis and stem cells in normal brain aging.  In Hof, P.R. and Mobbs, C.V. (Eds.) Handbook of the Neuroscience of Aging, Academic Press, New York, NY, Pages 61-64.

Rostkowski, A.B., Peterson, D.A., and Urban, J.H. (2009) Cell-specific expression of neuropeptide Y Y1 and Y5 receptor immunoreactivity in the rat basolateral amygdala. Journal of Comparative Neurology 517:166-176.

Peterson, D.A. (2010) Confocal Microscopy. In: Kompoliti, K., and Verhagen-Metman, L. (eds.) Encyclopedia of Movement Disorders, vol. 1, pp. 250-252, Oxford: Academic Press.

Peterson, D.A. (2010) Stereology. In: Kompoliti, K., and Verhagen-Metman, L. (eds.) Encyclopedia of Movement Disorders, vol. 3, pp. 168-170, Oxford: Academic Press.

Marr, R., Thomas, R.M., and Peterson, D.A. (2010) Insights into neurogenesis and aging: potential for therapy for neurodegenerative disease., Future Neurology 5(4):527-541.

Lazarov, O. Mattson, M., Peterson, D.A., Pimplikar, S., and van Praag, H. (2010) When neurogenesis encounters aging and disease., Trends in Neuroscience 33(12):569-79.

Encinas, J.M., Michurina, T., Tordo, J., Peterson, D.A., Fishell, G., Koulakov, A., and Enikolopov, G. (2010) Division-coupled astrocytic differentiation of neural stem cells drives age-related decline in neurogenesis.  Cell Stem Cell 8:566-579.  Cover Image

Bernal, G.M. and Peterson, D.A. (2011)  Phenotypic and gene expression modification with normal brain aging in GFAP-positive astrocytes and neural stem cells.  Aging Cell 10:466-482.  Cover Image

Shin, L. and Peterson, D.A. (2012)  Impaired therapeutic capacity of autologous stem cells in a model of type 2 diabetes.  Stem Cells Translational Medicine, 1:125-135.

Klempin, F., Marr, R., and Peterson, D.A. (2012)  Modification of Pax6 and Olig2 gene expression in adult hippocampal neurogenesis selectively induces stem cell fate and alters both neuronal and glial populations.  Stem Cells, 30(3):500-9.

Hafez, D.M., Huang, J.Y., Howlett, D.R., Masliah, E., Peterson, D.A., and Marr, R.A. (2012)  F-spondin gene transfer improves memory performance and reduces amyloid-β levels in mice.  Neuroscience, 223:465-72.

Shin, L. and Peterson, D.A. (2013)  Human mesenchymal stem cell grafts enhance normal and impaired wound healing by recruiting existing endogenous tissue stem/progenitor cells.  Stem Cell Translational Medicine 2:33-42.

Schmitz, C., Eastwood, B.S., Tappan, S.J., Glaser, J.R., Peterson, D.A., and Hof, P.R.  (2014) Current automated 3D cell detection methods are not a suitable replacement for manual stereologic cell counting.  Frontiers in Neuroanatomy 8:  Article 27.

Olivera-Pasilio, V., Peterson, D.A., and Castelló, M.E. (2014) Spatial distribution and cellular composition of adult brain proliferative zones in the teleost, Gymnotus omarorum, Frontiers in Neuroanatomy 8: Article 88. 

Peterson, D.A. (2014)  High-resolution quantitative histology by confocal stereology.,  In: Conn, M. and Cornea, A. (eds.)  Fluorescence Microscopy:  Super-Resolution and Other Novel Techniques, Academic Press (Oxford), pp. 171-184.

Bazarek, S. and Peterson, D.A. (2014) Prospects for engineering neurons from local neocortical cell populations as cell-mediated therapy for neurological disorders.  Journal of Comparative Neurology 522:2857-2876.


Life in Discovery
Neuroscience Faculty